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Phone: +335.61.28.50.47

Words  keys:

  • Xanthomonas

  • Pathogenesis

  • Plant immunity

Laurent Noël

Principal Investigator of the SIX team

Director of the LIPME

SIX

RESEARCH SUBJECTS

  • Plant pathology

  • Plant immunity

  • Microbiology

  • Molecular genetics of plants and bacteria

  • Molecular biology

TRAINING

  • 1993-1996 : Magister ENS Lyon

  • 1995-1996 : Master Plant molecular and cellular physiology

  • 1998-2001 : PhD, University Paris-Saclay

  • 2007 : Habilitation to conduct research, Université Aix-Marseille

RECENT FUNDING

  • ANR NEPHRON (2018-2023) : development, physiology and immunity of hydathodes

  • TULIP T3EX1 (2021) : recognitions of Xanthomonas type III effectors in cabbages and tomato

COLLABORATIONS

  • Boris Szurek, IRD Montpellier, France

  • Laurent Deslandes, LIPME, Toulouse, France

  • Lionel Navarro, IBENS, Paris, France

  • Patrick Laufs, INRAE Versailles, France

  • Nathalie Leonhardt, BIAM, Cadarache, France

  • Jonathan Jacobs, OSU, Ohio

  • Adam Bogdanove, Cornell University, Ithaca, NY

  • Thomas Lahaye, Tübingen university, Germany

  • Sylvestre Marillonnet, IPB, Halle/Saale, Germany

SCIENTIFIC PRODUCTION

CONNECTIONS

HOBBY

Sailing, Woodworking

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Phone: +335.61.28.50.47

Words  keys:

  • Xanthomonas

  • Virulence

  • HR

  • Type 3 secretion system

  •   Effectors

  •   Genomics

Matthieu Arlat

Professor at Toulouse III University

SIX

RESEARCH SUBJECTS

Comparative genomics of Xanthomonadaceae

TRAINING

  • PhD Université Toulouse III, Paul Sabatier, 1989

COLLABORATIONS

Marie-Agnès Jacques, Martial Briand, IRHS Angers

EDUCATION

  • Professor of Microbiology, Toulouse III University, Paul Sabatier

    • Bachelor: General Microbiologyb and Molecular Genetics

    • Master Biotechnology: Strategy in Microbiology, Diagnosis and Infectious Strategy

COMMITTEE MEMBER

  • Member of the Scientific Commission Sector 2 (Biological and Medical Sciences) of the IRD

  • Elected member of the CA of Toulouse III University, Paul Sabatier

SCIENTIFIC PRODUCTION

ORCID: 0000-0001-6196-4856

CONNECTIONS

HOBBY

  • Photography

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Phone: +335.61.28.50.47

Key words:

  • Xanthomonas 

  • Pathogenicity

  • Host-pathogen interaction

Alice Boulanger

Lecturer University Paul Sabatier - Toulouse III

SIX

RESEARCH SUBJECTS

During my career, I have studied the mechanisms and regulation of virulence in several models of host-pathogen interactions (plant and animal pathogens). 
Today, my project focuses on the study of genetic determinants of adaptation and pathogenesis of plant pathogens during infection, exploiting the new perspectives offered by recent "Omics" technologies. The project focuses on the Brassica black rot disease caused by the vascular pathogen Xanthomonas campestris pv. campestris (Xcc).

Trans

TRAINING

2009 : PhD, Plant-Microorganism Interactions 
           Paul Sabatier University, Toulouse III. 
2005 : Master's degree, Functional analysis of genomes, speciality microorganisms 
           University Paul Sabatier, Toulouse III. 

RECENT FUNDING

ANR grant XBOX (2020-2024): The making of a pathogen: How Xanthomonas adapts to plant environments

COLLABORATIONS

  • Adam Deutschbauer,  University of California, Berkeley, USA.

  • Jennifer Lewis, University of California, Berkeley, USA .

  • Caroline Baroukh, LIPME, INRAE, Auzeville, FRANCE.

EDUCATION

Lecturer at the University Paul Sabatier UT3.

My teaching activity is mainly in the field of microbiology at Licence 2 and Licence 3 levels. I am in charge of a general microbiology course common to both BCP and 2B2M courses, gathering about 500 students of Licence 2 at Paul Sabatier University. I am also involved in the international Master associated with this EUR (TULIP-GSR).

COMMITTEE MEMBER

Member of the TULIP pedagogical council (2016-2024)

SCIENTIFIC PRODUCTION

HOBBY

Climbing

OTHER AFFILIATION

American Society of Microbiology (ASM)

 
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Phone: +335.61.28.50.47

Key words :

  • Xanthomonas

  • TAL effectors

  • SWEET transporter

  • Black rot

  • Cauliflower

Corinne Audran

Researcher 

SIX

RESEARCH SUBJECTS

Most Xanthomonas bacteria translocate Transcription Activator-Like Effector (TALE) proteins inside plant cells using their type III secretion machinery. TALEs are a unique type of bacterial effector proteins that help the pathogen to exploit and modify the plant environment by directly and specifically inducing the expression of plant genes to the benefit of bacteria. TALE-mediated induction of a subset of genes, referred to as susceptibility genes, can promote host colonization and disease. Those genes could represent new sources of black rot resistance by loss of susceptibility. My project aims at studying the mechanisms by which TALEs mediate susceptibility to Xanthomonas in Brassicaceae.

TRAINING

Habilitation to Direct Research (HDR), University of Toulouse.

PhD from the University of Paris Sud-Orsay (Paris XI)

RECENT FUNDING

2021-2023 : phD fellowship (BAP INRAE/ LIPME)

COLLABORATIONS

  • Boris Szurek, IRD Montpellier, France

  • Adam Bogdanove, Cornell University, Ithaca, USA

  • Thomas Lahaye, Tübingen University, Germany

  • Rozenn Le Hir, INRAE Versailles, France

TEACHING

Interactions symbiotiques et pathogènes, Master II ADAM, Toulouse University

TICaBM « TechnIques et Champs d’application de la Biologie Moléculaire », Licence 3, BCP, Toulouse University

COMMITTEE MEMBER

  • Member of the scientific council of the SEVAB doctoral school

  • Member of the monitoring committee of PhD students from LIPME

SCIENTIFIC PRODUCTION

 
 
 
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Firstname name

Function

Team

Phone: +335.61.28.50.47

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Phone: +335.61.28.50.47

Emmanuelle Lauber

CNRS Researcher

SIX

RESEARCH SUBJECTS

  • Plant pathology

  • Microbiology

  • Molecular genetics of plants and bacteria

  • Molecular biology

TRAINING

  • 1992-1994 : Master of Biochemistry, University Louis Pasteur, Strasbourg

  • 1994-1995 : Postgraduate in Plant Biology, University Louis Pasteur, Strasbourg

  • 1995-1998 : PhD in virology, University Louis Pasteur, Strasbourg

  • 2007 : Habilitation à diriger les recherches, University Paul Sabatier, Toulouse

RECENT FUNDING

  • SPE (2022-2023) XanthoHS

COLLABORATIONS

  • Laurent Deslandes, LIPME, Toulouse, France

  • Sylvestre Marillonnet, IPB, Halle/Saale, Germany

COMMITTEE MEMBER

  • CDL

  • CLHSCT

SCIENTIFIC PRODUCTION

HOBBY

Horse riding, agility

 
 
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Phone: +335.61.28.50.47

Jean-Marc Routaboul

Research ingeneer

SIX

RESEARCH SUBJECTS

Hydathodes are openings on the leaf margin of most plants that release water during the process known as guttation. My current interest is to decipher the role of hydathodes especially in plant immunity combining transcriptomic, functional genomic and physiology.

Superficially hydathodes do look like stomata and until recently have lied very much in the shadow of their more high-profile, gas-exchange-controlling neighbours (Perrin, 1970). However, hydathodes host many biological functions that are also important for the whole plant (Cerutti et al., 2017, 2019). When the stomata are close, during the night for instance, excess water is discharged by this organ and is often mistaken with dew.  

 

Hydathode are a potential infection routes of a growing number of harmful microbes, including one that cause black rot on brassicaceae such as Arabidopsis and cauliflower, Xanthomonas campestris pv. Campestris.  

TRAINING

After a PhD in Plant Biology earned in Grenoble in 1991, I have worked on the model plant Arabidopsis using a combination of functional genomic, metabolomics and quantitative genetic approaches. I joined the group of J. Browse at Washington State University in 1994 to study for four years the role of plant polyunsaturated fatty acid for cold and heat stress tolerance. I went then to the group of C. Benning at IGF-Berlin for one year and continued this work from 1998 to 2001 in the team of L. Lepiniec at INRA Versailles where he was among the first to clone the DAGAT gene whose product catalyses the last step in oil synthesis (and fat).  I was hired at INRA in 2003 as a full-time research engineer in the group of L. Lepiniec. I developed there several projects dealing with flavonoid synthesis in Arabidopsis seed especially on the chemical identification of these still poorly studied metabolites and on the genetic bases of their variability. From 2012 to 2018, I moved to Toulouse and another model plant tomato to focus on the molecular mechanism leading to the development of fruit flesh at the Genomic and Biology of Fruit laboratory.

COLLABORATIONS

Gregory Mouille, Gilles Clément, INRAE, Versailles, France

Vincent Burlat, Alain Jauneau, LRSV, Toulouse, France

Lionel Navarro, IBENS, Paris, France

Patrick Laufs, INRAE Versailles, France

Nathalie Leonhardt, BIAM, Cadarache, France

Jonathan Jacobs, OSU, Ohio

SCIENTIFIC PRODUCTION

ORCID:0000-0003-2197-5280

 
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Phone: +335.61.28.50.47

Key words

Firstname name

Function

Team

RESEARCH SUBJECTS

Research topics

TRAINING

Recent funding

COLLABORATIONS

Collaborations

SCIENTIFIC PRODUCTION

Scientific productions

 
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Caroline Bellenot

PhD student

SIX

RESEARCH SUBJECTS

Xanthomonas campestris pv. campestris (Xcc) bacterium is the agent of black rot disease in Brassica. Xcc characteristic is its ability to enter its hosts through hydathodes, organs located at the border of leaves. From there, it can spread in the vascular system and infect the whole plant. Our team showed that hydathodes are involved in vascular immunity of Brassica (Cerutti et al., 2017). However, genetic basis of this immunity are not well known. Within the framework of the NEPHRON (ANR) project that funds my PhD project, I use transcriptomic, metabolomics, genetic and plant pathology approaches to characterize physiology and immunity of hydathodes.

Phone: +335.61.28.50.47

TRAINING

2018: Master’s degree in Plant biology, major in plant health (Angers University, France)

SCIENCE AND SOCIETY

Science communication in middle and high schools, to present science studies to students.

HOBBY

knitting, woodwork, coding

 
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Phone: +335.61.28.50.47

Thomas Quiroz-Monnens

PhD student

SIX

RESEARCH SUBJECTS

Genetic determinants of Xanthomonas campestris adaptation to the plant environment

TRAINING

Bsc Plant Science, Wageningen University and Research, Netherlands

Msc Plant Biotechnology, Wageningen University and Research, Netherlands

COMMITTEE MEMBER

SEVAB student representative

SCIENTIFIC PRODUCTION

Fire Blight Susceptibility in spp. Correlates to Sensitivity to Secreted Cell Death Inducing Compounds.  https://doi.org/10.3389/fpls.2021.660337

CONNECTIONS

 
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Phone: +335.61.28.50.47

Key words

Brice Charleux

PhD student

SIX

RESEARCH SUBJECTS

Xanthomonas bacteria are able to translocate TALE (Transcription Activator-Like Effector) proteins into plant cells to activate transcription of plant susceptibility (S) genes and promote disease. This is the case of Xanthomonas campestris pv. campestris (Xcc), the causal agent of black knot disease of Brassicas.
My PhD project aims to identify and characterize the S genes targeted by Xcc TALEs in cauliflower and Arabidopsis, with a particular focus on the SWEET (Sugar Will Eventually be Exported Transporter) gene families. The ultimate goal of this project is to generate new sources of resistance by loss of sensitivity in Brassicaceae

TRAINING

Master B2iPME (Integrative Biology of Plant, Microorganism and Environment Interactions), University of Bourgogne (Dijon).

COMMITTEE MEMBER

Member of the Research Committee at the University of Toulouse III Paul Sabatier